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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC37
All Species:
16.97
Human Site:
S289
Identified Species:
37.33
UniProt:
Q494V2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q494V2
NP_872434.2
611
71117
S289
L
K
K
A
K
E
V
S
E
A
S
K
E
S
S
Chimpanzee
Pan troglodytes
XP_516716
600
69770
S278
L
K
K
A
K
E
V
S
E
A
S
K
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001114297
608
70869
S289
L
K
N
A
K
E
I
S
E
A
S
K
D
G
S
Dog
Lupus familis
XP_851379
703
79265
T385
L
K
K
A
K
E
A
T
E
P
P
K
E
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80VN0
459
53845
T198
L
P
Q
V
G
Q
L
T
Q
L
S
P
H
S
E
Rat
Rattus norvegicus
XP_001076288
604
70773
T291
L
K
R
A
K
E
S
T
E
L
K
S
I
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509164
298
34913
T37
K
M
V
K
I
N
E
T
R
E
L
N
A
Q
V
Chicken
Gallus gallus
XP_425162
571
67562
E266
Q
L
K
T
A
D
K
E
S
A
S
E
K
S
L
Frog
Xenopus laevis
Q6NRC9
1030
118723
K653
I
I
E
A
E
R
F
K
E
V
K
D
G
F
D
Zebra Danio
Brachydanio rerio
NP_001070228
547
64075
G272
V
P
P
D
S
K
R
G
E
R
Q
T
A
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187699
537
62535
G268
S
R
S
S
M
S
K
G
V
G
K
P
S
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
91.9
57
N.A.
51.8
66.1
N.A.
27.9
41.4
20.7
38.6
N.A.
N.A.
N.A.
N.A.
41
Protein Similarity:
100
97.5
95.2
66.4
N.A.
62
80.3
N.A.
37.4
61.5
35.5
58.4
N.A.
N.A.
N.A.
N.A.
63.5
P-Site Identity:
100
100
73.3
60
N.A.
20
40
N.A.
0
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
73.3
N.A.
53.3
53.3
N.A.
6.6
46.6
33.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
55
10
0
10
0
0
37
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
0
0
0
0
10
10
0
10
% D
% Glu:
0
0
10
0
10
46
10
10
64
10
0
10
28
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
10
0
0
19
0
10
0
0
10
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
10
0
0
10
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
10
46
37
10
46
10
19
10
0
0
28
37
10
10
0
% K
% Leu:
55
10
0
0
0
0
10
0
0
19
10
0
0
10
19
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
19
10
0
0
0
0
0
0
10
10
19
0
0
0
% P
% Gln:
10
0
10
0
0
10
0
0
10
0
10
0
0
10
0
% Q
% Arg:
0
10
10
0
0
10
10
0
10
10
0
0
0
10
0
% R
% Ser:
10
0
10
10
10
10
10
28
10
0
46
10
10
37
28
% S
% Thr:
0
0
0
10
0
0
0
37
0
0
0
10
0
0
0
% T
% Val:
10
0
10
10
0
0
19
0
10
10
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _